Intrathecal Buprenorphine Induced Severe Respiratory Depression
نویسندگان
چکیده
منابع مشابه
Naloxone reversal of buprenorphine-induced respiratory depression.
BACKGROUND The objective of this investigation was to examine the ability of the opioid antagonist naloxone to reverse respiratory depression produced by the mu-opioid analgesic, buprenorphine, in healthy volunteers. The studies were designed in light of the claims that buprenorphine is relatively resistant to the effects of naloxone. METHODS In a first attempt, the effect of an intravenous b...
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We assessed the high incidence of pain after injection of methohexitone while conducting recent studies in out-patients using methohexitone and alfentanil. We tried a combination of two methods of solution of mcthohexitone alter reports that the use of normal saline rather than water reduced thc incidence of pain from 42"; to 16",,,' and that pretreatment with lignocaine 10 mg rcduced the incid...
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Buprenorphine is a potent, semi-synthetic opioid analgesic derived from thebaine. The drug displays the characteristics of an agonist at the mu receptors and antagonist at the kappa receptors. Although buprenorphine has shown some pharmacological effects on delta and kappa opioid receptors, the action on the mu receptors appears to be responsible for most of the analgesic effects associated wit...
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Buprenorphine is a mixed opioid receptor agonist-antagonist used in acute and chronic pain management. Although this agent's analgesic effect increases in a dose-dependent manner, buprenorphine-induced respiratory depression shows a marked ceiling effect at higher doses, which is considered to be an indicator of safety. Nevertheless, cases of overdose mortality or severe respiratory depression ...
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Background: General anesthesia draw the most commonly used modalities for post cesarean delivery pain relief is systemic administration of opioids, while the administration of small dose of intrathecal opioid during spinal anesthesia can be a possible alternative. The aim of this study was to evaluate the effects of buprenorphine on cesarean section prescribed intrathecally. Methods: In this d...
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ژورنال
عنوان ژورنال: IOSR Journal of Dental and Medical Sciences
سال: 2014
ISSN: 2279-0861,2279-0853
DOI: 10.9790/0853-131134344